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KMID : 0043319840070020109
Archives of Pharmacal Research
1984 Volume.7 No. 2 p.109 ~ p.113
Surface Activity of Crude Ginseng Saponin
Han SK
Kim NH
Abstract
The critical micelle concentration (CMC) of crude ginseng saponin in water was determined by fluorometry and surface-tension measurement. These two methods gave the CMC value, 0.015g/100ml and 0.013g/100ml, respectively. The surface excess of the saponin and the area occupied by a saponin molecule at the monolayer adsorbed at air and waterinterface were calculated employing Gibbs adsorption equation. The presence of salt increased the surface activity of the saponin: it decreased the CMC, the surface tension at the CMC and the area occupied by a saponin molecule at the monolayer, which should be due to the salting-out effect of the salt.
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